Which non-APP BACE1 substrates explain cognitive worsening or toxicity in failed BACE inhibitor trials?

Evidence span

Which non-APP BACE1 substrates explain cognitive worsening or toxicity in failed BACE inhibitor trials?

Method & conditions

Evidence type

theoretical

Method

manual state transition

Conditions

Candidate gap for maintainer review; not a guaranteed experiment target.

Replicated

not yet

Confidence basis

operator-supplied frontier prior; review required