Systematic in silico analysis of clinically tested drugs for reducing amyloid-beta plaque accumulation in Alzheimer's disease.

Evidence span

Systematic in silico analysis of clinically tested drugs for reducing amyloid-beta plaque accumulation in Alzheimer's disease.

From Madrasi K et al. 2021, Alzheimer's & dementia : the journal of the Alzheimer's Association

Method & conditions

Evidence type

computational

Method

manual state transition

Species

Homo sapiens

Conditions

Humans; Alzheimer Disease; Pharmaceutical Preparations; Computer Simulation; Amyloid Precursor Protein Secretases — Alzheimer's & dementia : the journal of the Alzheimer's Association 2021

Replicated

not yet

Confidence basis

operator-supplied frontier prior; review required