Efficacy and <i>APOE</i> ε4-stratified risk of donanemab in Alzheimer's disease: A systematic review and meta-analysis of randomized clinical trials.

Evidence span

Efficacy and <i>APOE</i> ε4-stratified risk of donanemab in Alzheimer's disease: A systematic review and meta-analysis of randomized clinical trials.

From Pereira da Silva AM et al. 2025, Journal of Alzheimer's disease : JAD

Method & conditions

Evidence type

meta_analysis

Method

manual state transition; placebo-controlled clinical trial where source reports control arm

Species

Homo sapiens

Conditions

Humans; Alzheimer Disease; Treatment Outcome; Apolipoprotein E4; Randomized Controlled Trials as Topic — Journal of Alzheimer's disease : JAD 2025

Replicated

not yet

Confidence basis

operator-supplied frontier prior; review required